Senise rises on a hill, at the point where the creek meets the river Serrapotamo Sinni.

Famous for being the front door of the Pollino National Park, the settlement was founded in Roman times as evidenced by the remains of a villa found in the San Filippo area. In 1916. during some excavations in the district Salsa, a series of Barbaric era tombs were discovered. The valuable golden objects found there are now preserved in the National Archaeological Museum of Naples, with the name "Ori di Senise.
The historic center is divided into a series of streets, alleys and open spaces through which we reach the imposing medieval castle, built in the thirteenth century and renovated in the fifteenth century.
Interesting is also the Church of San Francesco, built in the early years of 1200, within which are preserved paintings, frescoes and statues dating from the XIII and XIV century, a Gothic portal, a fine altarpiece by Simone from Florence, a wooden crucifix , a wooden choir created by local artisans and a wooden pulpit.
Not to miss: former Capuccini monastery (1596), the Municipal Palace (cloister of the Church of San Francesco), the Municipal Archaeological Museum, the Ethnological Museum of Arts and Civilization of the farmers and artisans of Senise. Of great interest the Dam area of Monte Cotugno, built in the seventies, is the largest hard ground dam of Europe, whose waters are used for the irrigation needs of most of the Pontine area and most of the other areas in Puglia.