Vecchiano rises on the Pisan plain, along the right bank of the Serchio river, in an area inhabited since the Etruscan period. It was mentioned for the first time in a document of 762.
Owing to its strategic position at the boundary between the domains of Lucca and those ones of Pisa, the village subdued the siege by the Pisan troops who conquered the territory and built a castle. Between the XIII and XIV century the territory of Vecchiano subdued the consequences of the struggles fought between Pisa and Lucca, wanting this latter to take again the control of its ancient possession. At that time Vecchiano also subdued numerous sacks and devastations caused by the troops coming from the Milan Dukedom. After the long period of the Pisan domination, in 1406 the village of Vecchiano entered the domains of the Republic of Florence under the Medici's noble family.
Among the most important monument of the town, we have to mention the Cloch Tower, the Etrusca Fortress, built on the upper part of Vecchiano, surrounded by the ancient walls yet, the Sanctuary of Santa Maria delle Grazie in castello, so called by Leonardo Da Vinci and built on a rocky promontory overlooking the town, and the remains of the Avane Castle.